Hydrochloric Acid → Ethyl 2-benzyl-3-(4-methoxyphenyl)propionate

HRID 2137071Notes

Reaction equation

HRID 2137071 reaction equation
[Br:28][CH2:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:13][O:14][c:15]1[cH:16][cH:17][c:18]([CH2:21][CH2:22][C:23](=[O:24])[O:25][CH2:26][CH3:27])[cH:19][cH:20]1.[CH3:43][N:44]([CH3:45])[P:46](=[O:47])([N:48]([CH3:49])[CH3:50])[N:51]([CH3:52])[CH3:53].[CH3:54][CH2:55][CH2:56][CH2:57][CH2:58][CH3:59].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[ClH:36].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1.[OH2:42]>>[CH3:13][O:14][c:15]1[cH:16][cH:17][c:18]([CH2:21][CH:22]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[CH2:29][c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:19][cH:20]1

Participants

10

Reactant 9

HCID 313Hydrochloric AcidHCID 962WaterHCID 7498Benzyl BromideHCID 7912DiisopropylamineHCID 8028TetrahydrofuranHCID 8058HexaneHCID 12679HexamethylphosphoramideHCID 348843Ethyl 3-(4-methoxyphenyl)propanoateHCID 178418339Butyllithium

Product 1

HCID 15714011Ethyl 2-benzyl-3-(4-methoxyphenyl)propionate

Sources & evidence

ORD record
ord-57b11dabb60e42d487f92f8518baac06
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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