Chloride → 2-(5-Fluoro-2-{[4'-(trifluoromethyl)-1,1'-biphenyl-4-yl]methoxy}phenyl)ethylamine
Reaction equation
[Al+3:30].[Al+3:38].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[Cl-:35].[Cl-:36].[Cl-:37].[F:1][c:2]1[cH:3][cH:4][c:5]([O:11][CH2:12][c:13]2[cH:14][cH:15][c:16](-[c:19]3[cH:20][cH:21][c:22]([C:25]([F:26])([F:27])[F:28])[cH:23][cH:24]3)[cH:17][cH:18]2)[c:6]([CH2:8][C:9]#[N:10])[cH:7]1.[H-:29].[H-:32].[H-:33].[H-:34].[Li+:31].[Na+:40].[OH-:39]>>[F:1][c:2]1[cH:3][cH:4][c:5]([O:11][CH2:12][c:13]2[cH:14][cH:15][c:16](-[c:19]3[cH:20][cH:21][c:22]([C:25]([F:26])([F:27])[F:28])[cH:23][cH:24]3)[cH:17][cH:18]2)[c:6]([CH2:8][CH2:9][NH2:10])[cH:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-7836d8e3356347e79995c3c216fdaff8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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