Tetrahydrofuran → 4-(tert-Butyldimethylsilanyloxy)-1-(7-methoxybenzofuran-2-yl)-butan-1-ol
Reaction equation
[Br:2][CH2:3][CH2:4][CH2:5][O:6][Si:7]([CH3:8])([CH3:9])[C:10]([CH3:11])([CH3:12])[CH3:13].[CH3:15][O:16][c:17]1[cH:18][cH:19][cH:20][c:21]2[cH:22][c:23]([CH:26]=[O:27])[o:24][c:25]12.[I:14].[Mg:1].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[CH2:3]([CH2:4][CH2:5][O:6][Si:7]([CH3:8])([CH3:9])[C:10]([CH3:11])([CH3:12])[CH3:13])[CH:26]([c:23]1[cH:22][c:21]2[cH:20][cH:19][cH:18][c:17]([O:16][CH3:15])[c:25]2[o:24]1)[OH:27]Participants
6
Sources & evidence
- ORD record
- ord-11a47def758f4637bc42fe8ea8fdde20
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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