Dibromodifluoromethane → 4-{1-[1-(3-bromophenyl)-4,4-difluorobut-3-en-1-yl]-1H-pyrazol-4-yl}-7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH:8]([CH2:9][CH:10]=[O:11])[n:12]2[n:13][cH:14][c:15](-[c:17]3[c:18]4[c:19]([n:20][cH:21][n:22]3)[n:23]([CH2:26][O:27][CH2:28][CH2:29][Si:30]([CH3:31])([CH3:32])[CH3:33])[cH:24][cH:25]4)[cH:16]2)[cH:5][cH:6][cH:7]1.[Br:59][C:60]([F:61])([F:62])[Br:63].[CH2:64]1[O:65][CH2:66][CH2:67][CH2:68]1.[CH3:34][N:35]([CH3:36])[C:37](=[O:38])[CH3:39].[Zn:69].[c:40]1([P:41]([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[cH:54][cH:55][cH:56][cH:57][cH:58]1>>[Br:1][c:2]1[cH:3][c:4]([CH:8]([CH2:9][CH:10]=[C:60]([F:61])[F:62])[n:12]2[n:13][cH:14][c:15](-[c:17]3[c:18]4[c:19]([n:20][cH:21][n:22]3)[n:23]([CH2:26][O:27][CH2:28][CH2:29][Si:30]([CH3:31])([CH3:32])[CH3:33])[cH:24][cH:25]4)[cH:16]2)[cH:5][cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-a21d59511bd043febf7ef70b0d9816a2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…