Water → tert-Butyl 4-cyano-4-isopropylpiperidine-1-carboxylate

HRID 2140147Notes

Reaction equation

HRID 2140147 reaction equation
[CH3:29][N:30]([CH3:31])[CH:32]=[O:33].[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[Cl:20][c:21]1[n:22][c:23]([Cl:24])[n:25][c:26]([Cl:27])[n:28]1.[NH2:1][C:2](=[O:3])[C:4]1([CH:17]([CH3:18])[CH3:19])[CH2:5][CH2:6][N:7]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:8][CH2:9]1.[OH2:34]>>[N:1]#[C:2][C:4]1([CH:17]([CH3:18])[CH3:19])[CH2:5][CH2:6][N:7]([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH2:8][CH2:9]1

Participants

6

Reactant 5

HCID 962WaterHCID 6228DimethylformamideHCID 7954Cyanuric chlorideHCID 8857Ethyl AcetateHCID 68728193tert-Butyl 4-carbamoyl-4-isopropylpiperidine-1-carboxylate

Product 1

HCID 68787901tert-Butyl 4-cyano-4-isopropylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-88c5448902b24b4e9f66ac1fd2148d2f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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