Acetic Acid → Cyclohexyl-[2-(2,6-dimethoxy-pyridin-3-yl)-5,6-difluoro-benzoimidazol-1-yl]-acetic acid
Reaction equation
[CH2:1]([N:2]([N:3]=[O:4])[C:9]([CH:10]([n:11]1[c:12](-[c:22]2[c:23]([O:30][CH3:31])[n:24][c:25]([O:28][CH3:29])[cH:26][cH:27]2)[n:13][c:14]2[c:15]1[cH:16][c:17]([F:21])[c:18]([F:20])[cH:19]2)[CH:32]1[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37]1)=[O:38])[c:5]1[cH:6][cH:7][cH:8][cH:39][cH:40]1.[CH3:46][C:47]([OH:48])=[O:49].[Li+:43].[O:50]1[CH2:51][CH2:52][CH2:53][CH2:54]1.[OH-:42].[OH2:41].[OH2:55].[OH:44][OH:45]>>[C:9]([CH:10]([n:11]1[c:12](-[c:22]2[c:23]([O:30][CH3:31])[n:24][c:25]([O:28][CH3:29])[cH:26][cH:27]2)[n:13][c:14]2[c:15]1[cH:16][c:17]([F:21])[c:18]([F:20])[cH:19]2)[CH:32]1[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37]1)([OH:38])=[O:48]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-4445c520a3cd45de987c110873cc1ecd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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