Potassium Cation → 3-(2-Fluorophenyl)pyridine

HRID 2140334Notes

Reaction equation

HRID 2140334 reaction equation
[Br:1][c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1.[C:20]([P:21]([C:22]([CH3:23])([CH3:24])[CH3:25])[C:26]([CH3:27])([CH3:28])[CH3:29])([CH3:30])([CH3:31])[CH3:32].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[F-:18].[F:8][c:9]1[c:10]([B:15]([OH:16])[OH:17])[cH:11][cH:12][cH:13][cH:14]1.[K+:19].[O:38]1[CH2:39][CH2:40][O:41][CH2:42][CH2:43]1.[O:46]=[C:47]([CH:48]=[CH:49][c:50]1[cH:51][cH:52][cH:53][cH:54][cH:55]1)[CH:56]=[CH:57][c:58]1[cH:59][cH:60][cH:61][cH:62][cH:63]1.[O:64]=[C:65]([CH:66]=[CH:67][c:68]1[cH:69][cH:70][cH:71][cH:72][cH:73]1)[CH:74]=[CH:75][c:76]1[cH:77][cH:78][cH:79][cH:80][cH:81]1.[O:82]=[C:83]([CH:84]=[CH:85][c:86]1[cH:87][cH:88][cH:89][cH:90][cH:91]1)[CH:92]=[CH:93][c:94]1[cH:95][cH:96][cH:97][cH:98][cH:99]1.[Pd:44].[Pd:45]>>[c:2]1(-[c:10]2[c:9]([F:8])[cH:14][cH:13][cH:12][cH:11]2)[cH:3][n:4][cH:5][cH:6][cH:7]1

Participants

10

Reactant 9

HCID 813Potassium CationHCID 8028TetrahydrofuranHCID 122863-BromopyridineHCID 23938Palladium2×HCID 28179Fluoride IonHCID 312751,4-DioxaneHCID 83681Tris(1,1-dimethylethyl)phosphineHCID 95417Dibenzylidene acetone3×HCID 27343542-Fluorophenylboronic acid

Product 1

HCID 132706453-(2-Fluorophenyl)pyridine

Sources & evidence

ORD record
ord-d70ff3766318413bb2e887f871d36e18
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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