Dimethyl Sulfoxide → 4-(Benzyloxy)-2-methylaniline

HRID 2140989Notes

Reaction equation

HRID 2140989 reaction equation
[Br:12][CH2:13][c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1.[C:25]([O:26][CH2:27][CH3:28])(=[O:29])[CH3:30].[CH2:42]([O:43][CH2:44][CH3:45])[CH3:46].[CH3:21][S:22]([CH3:23])=[O:24].[CH3:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36].[H-:10].[NH2:1][c:2]1[c:3]([CH3:9])[cH:4][c:5]([OH:8])[cH:6][cH:7]1.[Na+:11].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1.[OH2:20]>>[NH2:1][c:2]1[c:3]([CH3:9])[cH:4][c:5]([O:8][CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[cH:6][cH:7]1

Participants

11

Reactant 10

HCID 679Dimethyl SulfoxideHCID 923Sodium ionHCID 962WaterHCID 3283Diethyl EtherHCID 7498Benzyl BromideHCID 8028TetrahydrofuranHCID 8058HexaneHCID 8857Ethyl AcetateHCID 178194-Amino-m-cresolHCID 166653Hydride

Product 1

HCID 167730534-(Benzyloxy)-2-methylaniline

Sources & evidence

ORD record
ord-38ef5dce613c4906a9be8b6356cf7265
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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