Tetrahydrofuran → [4-(4-Nitrophenyl)but-3-ynyl]carbamic acid tert-butyl ester

HRID 2141301Notes

Reaction equation

HRID 2141301 reaction equation
[C:16]([CH3:17])([CH3:18])([CH3:19])[O:20][C:21]([NH:22][CH2:23][CH2:24][C:25]#[CH:26])=[O:27].[CH2:1]1[O:2][CH2:3][CH2:4][CH2:5]1.[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[Cu:28][I:29].[I:6][c:7]1[cH:8][cH:9][c:10]([N+:13](=[O:14])[O-:15])[cH:11][cH:12]1>>[c:7]1([C:26]#[C:25][CH2:24][CH2:23][NH:22][C:21]([O:20][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:27])[cH:8][cH:9][c:10]([N+:13](=[O:14])[O-:15])[cH:11][cH:12]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 124951-Iodo-4-nitrobenzeneHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 10725815tert-Butyl 3-butyn-1-ylcarbamate

Product 1

HCID 11716220[4-(4-Nitrophenyl)but-3-ynyl]carbamic acid tert-butyl ester

Sources & evidence

ORD record
ord-9abe58f6952846f6a64a02874f602f5a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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