Hydrochloric Acid → 1-benzyl-N-methylpiperidin-4-amine

HRID 2142239Notes

Reaction equation

HRID 2142239 reaction equation
[BH4-:23].[CH3:16][NH2:17].[CH3:18][O-:19].[CH3:29][OH:30].[CH:25]([OH:26])([CH3:27])[CH3:28].[ClH:15].[Na+:20].[Na+:22].[Na+:24].[OH-:21].[c:1]1([CH2:7][N:8]2[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH2:7][N:8]2[CH2:9][CH2:10][CH:11]([NH:17][CH3:16])[CH2:12][CH2:13]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

10

Reactant 9

HCID 313Hydrochloric AcidHCID 887MethanolHCID 923Sodium ion3×HCID 961HydroxideHCID 3776IsopropanolHCID 6329MethylamineHCID 192201-Benzyl-4-piperidoneHCID 28123BorohydrideHCID 3826051Methoxide

Product 1

HCID 41361281-benzyl-N-methylpiperidin-4-amine

Sources & evidence

ORD record
ord-76f8135cfe07443d904ff1ad6bd54de2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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