Acetate → 8-(1-Ethyl-propyl)-2,6-dimethyl-3-{2,6-dimethyl-imidazo[1,2-b]pyridazin-3-yl}imidazo[1,2-b]pyridazine

HRID 2143631Notes

Reaction equation

HRID 2143631 reaction equation
[C:48](=[O:49])([O-:50])[O-:51].[CH2:12]([CH3:13])[CH:14]([CH2:15][CH3:16])[c:17]1[c:18]2[n:19]([n:20][c:21]([CH3:23])[cH:22]1)[c:24]([I:28])[c:25]([CH3:27])[n:26]2.[CH3:1][c:2]1[n:3][c:4]2[n:5]([n:6][c:7]([CH3:10])[cH:8][cH:9]2)[cH:11]1.[CH3:59][CH2:60][O:61][C:62]([CH3:63])=[O:64].[Cs+:52].[Cs+:53].[O-:66][C:67]([CH3:68])=[O:69].[O-:70][C:71]([CH3:72])=[O:73].[O:54]=[CH:55][N:56]([CH3:57])[CH3:58].[Pd+2:65].[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1>>[CH3:1][c:2]1[n:3][c:4]2[n:5]([n:6][c:7]([CH3:10])[cH:8][cH:9]2)[c:11]1-[c:24]1[n:19]2[c:18]([c:17]([CH:14]([CH2:12][CH3:13])[CH2:15][CH3:16])[cH:22][c:21]([CH3:23])[n:20]2)[n:26][c:25]1[CH3:27]

Participants

10

Reactant 9

HCID 175Acetate2×HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 11776TriphenylphosphineHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 218176672,6-Dimethylimidazo[1,2-b]pyridazineHCID 577526818-(1-Ethyl-propyl)-3-iodo-2,6-dimethyl-imidazo[1,2-b]pyridazine

Product 1

HCID 688572858-(1-Ethyl-propyl)-2,6-dimethyl-3-{2,6-dimethyl-imidazo[1,2-b]pyridazin-3-yl}imidazo[1,2-b]pyridazine

Sources & evidence

ORD record
ord-ed753c207645454fba1592c32fb7dda6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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