Bromide ion → 2-(4-Prop-2-ynyl-benzyloxy)-pyridine

HRID 2145793Notes

Reaction equation

HRID 2145793 reaction equation
[Br-:7].[C:27](=[O:28])([O-:29])[O-:30].[CH2:8]([Mg+:9])[CH3:10].[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[CH:6].[CH3:38][OH:39].[Cl:11][CH2:12][c:13]1[cH:14][cH:15][c:16]([CH2:17][O:18][c:19]2[n:20][cH:21][cH:22][cH:23][cH:24]2)[cH:25][cH:26]1.[Cu:40][Br:41].[K+:31].[K+:32].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1>>[C:5](#[CH:6])[CH2:12][c:13]1[cH:14][cH:15][c:16]([CH2:17][O:18][c:19]2[n:20][cH:21][cH:22][cH:23][cH:24]2)[cH:25][cH:26]1

Participants

10

Reactant 9

HCID 259Bromide ionHCID 813Potassium Cation2×HCID 887MethanolHCID 8028TetrahydrofuranHCID 19660Carbonate IonHCID 24593copper(I) bromideHCID 66111TrimethylsilylacetyleneHCID 592550952-(4-Chloromethyl-benzyloxy)-pyridineHCID 178461628HCID 178461628, compound

Product 1

HCID 592553112-(4-Prop-2-ynyl-benzyloxy)-pyridine

Sources & evidence

ORD record
ord-00b1654edef04835ba606c46d4d39763
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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