Hydrochloric Acid → 1,4-Diphenylpiperidine-4-carbonitrile
Reaction equation
[Br:16][c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1.[CH3:23][C:24]([CH3:25])([O-:26])[CH3:27].[CH3:51][c:52]1[cH:53][cH:54][cH:55][cH:56][cH:57]1.[ClH:1].[Na+:28].[O:61]=[C:62]([CH:63]=[CH:64][c:65]1[cH:66][cH:67][cH:68][cH:69][cH:70]1)[CH:71]=[CH:72][c:73]1[cH:74][cH:75][cH:76][cH:77][cH:78]1.[O:79]=[C:80]([CH:81]=[CH:82][c:83]1[cH:84][cH:85][cH:86][cH:87][cH:88]1)[CH:89]=[CH:90][c:91]1[cH:92][cH:93][cH:94][cH:95][cH:96]1.[O:97]=[C:98]([CH:99]=[CH:100][c:101]1[cH:102][cH:103][cH:104][cH:105][cH:106]1)[CH:107]=[CH:108][c:109]1[cH:110][cH:111][cH:112][cH:113][cH:114]1.[OH2:58].[Pd:59].[Pd:60].[c:29]1([CH3:30])[cH:31][cH:32][cH:33][cH:34][c:35]1[P:36]([c:37]1[cH:38][cH:39][cH:40][cH:41][c:42]1[CH3:43])[c:44]1[cH:45][cH:46][cH:47][cH:48][c:49]1[CH3:50].[c:2]1([C:8]2([C:14]#[N:15])[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[c:2]1([C:8]2([C:14]#[N:15])[CH2:9][CH2:10][N:11]([c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[CH2:12][CH2:13]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1Participants
11
Reactant 10
Product 1
Sources & evidence
- ORD record
- ord-be06915165cf42c4b3d11f8b14aabd2f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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