Tetrahydrofuran → 4-(2-Tert-butyl-4-nitrothiophene-5-carbonyl)-1-(2-(dimethylamino)ethyl)-3,3-dimethylpiperazin-2-one
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([N+:13](=[O:14])[O-:15])[c:8]([C:10](=[O:11])[OH:12])[s:9]1.[CH2:16]1[O:17][CH2:18][CH2:19][CH2:20]1.[CH3:21][N:22]([CH2:23][CH2:24][N:25]1[C:26](=[O:33])[C:27]([CH3:31])([CH3:32])[NH:28][CH2:29][CH2:30]1)[CH3:34].[CH3:48][CH2:49][O:50][C:51](=[O:52])[CH3:53].[CH:35]([N:36]([CH2:37][CH3:38])[CH:39]([CH3:40])[CH3:41])([CH3:42])[CH3:43].[S:44]([Cl:45])([Cl:46])=[O:47]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([N+:13](=[O:14])[O-:15])[c:8]([C:10](=[O:12])[N:28]2[C:27]([CH3:31])([CH3:32])[C:26](=[O:33])[N:25]([CH2:24][CH2:23][N:22]([CH3:21])[CH3:34])[CH2:30][CH2:29]2)[s:9]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-32868a82c8234acdbaab07fb5f790f2e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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