Water → 2-{[1-(2-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]oxy}-3-methoxy-N-(5-methylpyridin-2-yl)propanamide
Reaction equation
[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:2][Si:3]([N-:4][Si:5]([CH3:6])([CH3:7])[CH3:8])([CH3:9])[CH3:10].[CH3:49][CH2:50][O:51][C:52]([CH3:53])=[O:54].[Cl:26][c:27]1[c:28]2[c:29]([n:30][cH:31][n:32]1)[n:33](-[c:36]1[c:37]([Cl:42])[cH:38][cH:39][cH:40][cH:41]1)[n:34][cH:35]2.[Li+:1].[OH2:43].[OH:11][CH:12]([C:13](=[O:14])[NH:15][c:16]1[n:17][cH:18][c:19]([CH3:22])[cH:20][cH:21]1)[CH2:23][O:24][CH3:25]>>[O:11]([CH:12]([C:13](=[O:14])[NH:15][c:16]1[n:17][cH:18][c:19]([CH3:22])[cH:20][cH:21]1)[CH2:23][O:24][CH3:25])[c:27]1[c:28]2[c:29]([n:30][cH:31][n:32]1)[n:33](-[c:36]1[c:37]([Cl:42])[cH:38][cH:39][cH:40][cH:41]1)[n:34][cH:35]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-137fca6e4e6c4af8a55e5b13a514b03f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…