Hydrochloric Acid → 3-methoxy-N-methoxy-N-methyl-4-(trifluoromethyl)benzamide

HRID 2152056Notes

Reaction equation

HRID 2152056 reaction equation
[C:52](=[O:53])([O-:54])[OH:55].[CH3:2][NH:3][O:4][CH3:5].[CH3:32][N:33]([CH3:34])[CH2:35][CH2:36][CH2:37][N:38]=[C:39]=[N:40][CH2:41][CH3:42].[CH3:6][O:7][c:8]1[cH:9][c:10]([C:11](=[O:12])[OH:13])[cH:14][cH:15][c:16]1[C:17]([F:18])([F:19])[F:20].[CH:43]([N:44]([CH2:45][CH3:46])[CH:47]([CH3:48])[CH3:49])([CH3:50])[CH3:51].[Cl:57][CH2:58][Cl:59].[ClH:1].[ClH:31].[Na+:56].[OH:21][n:22]1[c:23]2[cH:24][cH:25][cH:26][cH:27][c:28]2[n:29][n:30]1>>[CH3:2][N:3]([O:4][CH3:5])[C:11]([c:10]1[cH:9][c:8]([O:7][CH3:6])[c:16]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:14]1)=[O:13]

Participants

10

Reactant 9

HCID 313Hydrochloric Acid2×HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6344DichloromethaneHCID 14232N,O-DimethylhydroxylamineHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 179641303-Methoxy-4-(trifluoromethyl)benzoic acid

Product 1

HCID 179640593-methoxy-N-methoxy-N-methyl-4-(trifluoromethyl)benzamide

Sources & evidence

ORD record
ord-d81e9c096c36488bb0fdaaf92b2dab34
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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