Dimethylformamide → 2-[3-(4-methoxyphenyl)-4-oxo-10-propoxy-7,8-dihydro-4H,6H-5-oxa-1-aza-phenanthren-1-yl]-N-(2-morpholin-4-ylethyl)acetamide

HRID 2152161Notes

Reaction equation

HRID 2152161 reaction equation
[CH3:15][O:16][c:17]1[cH:18][cH:19][c:20](-[c:23]2[cH:24][n:25]([CH2:42][C:43](=[O:44])[OH:45])[c:26]3[c:27]([O:38][CH2:39][CH2:40][CH3:41])[cH:28][c:29]4[c:34]([c:35]3[c:36]2=[O:37])[O:33][CH2:32][CH2:31][CH2:30]4)[cH:21][cH:22]1.[CH3:70][CH2:71][N:72]([CH2:73][CH3:74])[CH2:75][CH3:76].[F:46][P-:47]([F:48])([F:49])([F:50])([F:51])[F:52].[NH2:1][CH2:2][CH2:3][N:4]1[CH2:5][CH2:6][O:7][CH2:8][CH2:9]1.[O:10]=[CH:11][N:12]([CH3:13])[CH3:14].[n:53]1([O:54][C:55]([N:56]([CH3:57])[CH3:58])=[N+:59]([CH3:60])[CH3:61])[c:62]2[n:63][cH:64][cH:65][cH:66][c:67]2[n:68][n:69]1>>[NH:1]([CH2:2][CH2:3][N:4]1[CH2:5][CH2:6][O:7][CH2:8][CH2:9]1)[C:43]([CH2:42][n:25]1[cH:24][c:23](-[c:20]2[cH:19][cH:18][c:17]([O:16][CH3:15])[cH:22][cH:21]2)[c:36](=[O:37])[c:35]2[c:26]1[c:27]([O:38][CH2:39][CH2:40][CH3:41])[cH:28][c:29]1[c:34]2[O:33][CH2:32][CH2:31][CH2:30]1)=[O:44]

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 9886HexafluorophosphateHCID 4082852-MorpholinoethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 58492449HCID 58492449, compound

Product 1

HCID 674604752-[3-(4-methoxyphenyl)-4-oxo-10-propoxy-7,8-dihydro-4H,6H-5-oxa-1-aza-phenanthren-1-yl]-N-(2-morpholin-4-ylethyl)acetamide

Sources & evidence

ORD record
ord-7c45c149e7fc498fafcf5304346f1eb5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…