Dimethylformamide → N-{5-[(cyclopropylcarbonyl)amino]-2-methylphenyl}-1-(2,6-dichlorophenyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide

HRID 2152790Notes

Reaction equation

HRID 2152790 reaction equation
[CH3:71][CH2:72][O:73][C:74]([CH3:75])=[O:76].[CH:57]([N:58]([CH2:59][CH3:60])[CH:61]([CH3:62])[CH3:63])([CH3:64])[CH3:65].[Cl:1][c:2]1[c:3](-[n:9]2[cH:10][c:11]([C:16](=[O:17])[OH:18])[cH:12][cH:13][c:14]2=[O:15])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[NH2:19][c:20]1[cH:21][c:22]([NH:27][C:28](=[O:29])[CH:30]2[CH2:31][CH2:32]2)[cH:23][cH:24][c:25]1[CH3:26].[O:66]=[CH:67][N:68]([CH3:69])[CH3:70].[P-:33]([F:34])([F:35])([F:36])([F:37])([F:38])[F:39].[n:40]1([O:41][C:42]([N:43]([CH3:44])[CH3:45])=[N+:46]([CH3:47])[CH3:48])[c:49]2[n:50][cH:51][cH:52][cH:53][c:54]2[n:55][n:56]1>>[Cl:1][c:2]1[c:3](-[n:9]2[cH:10][c:11]([C:16](=[O:18])[NH:19][c:20]3[cH:21][c:22]([NH:27][C:28](=[O:29])[CH:30]4[CH2:31][CH2:32]4)[cH:23][cH:24][c:25]3[CH3:26])[cH:12][cH:13][c:14]2=[O:15])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 24693537N-(3-amino-4-methylphenyl)cyclopropanecarboxamideHCID 655011901-(2,6-Dichlorophenyl)-6-oxo-1,6-dihydro-3-pyridinecarboxylic acid

Product 1

HCID 59234680N-{5-[(cyclopropylcarbonyl)amino]-2-methylphenyl}-1-(2,6-dichlorophenyl)-6-oxo-1,6-dihydro-3-pyridinecarboxamide

Sources & evidence

ORD record
ord-93a118bb6cb9425e82664d839c887ac3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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