Hydrochloric Acid → 2-Chloro-N-[1-[(3,4-difluorophenyl)methyl]-piperidin-4-yl]-acetamide
Reaction equation
[CH3:25][CH2:26][O:27][C:28](=[O:29])[CH3:30].[Cl:19][CH2:20][C:21](=[O:22])[Cl:23].[ClH:1].[ClH:2].[F:3][c:4]1[cH:5][c:6]([CH2:11][N:12]2[CH2:13][CH2:14][CH:15]([NH2:18])[CH2:16][CH2:17]2)[cH:7][cH:8][c:9]1[F:10].[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1.[OH2:24]>>[F:3][c:4]1[cH:5][c:6]([CH2:11][N:12]2[CH2:13][CH2:14][CH:15]([NH:18][C:21]([CH2:20][Cl:19])=[O:22])[CH2:16][CH2:17]2)[cH:7][cH:8][c:9]1[F:10]Participants
7
Sources & evidence
- ORD record
- ord-bdd26e8215504b27b50c9719a463148a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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