Hydrochloric Acid → 2,2,2-Trifluoro-N-phenylacetamide

HRID 2154465Notes

Reaction equation

HRID 2154465 reaction equation
[Br:1][c:2]1[c:3]([NH:4][C:5]([C:6]([F:7])([F:8])[F:9])=[O:10])[cH:11][cH:12][cH:13][cH:14]1.[C:17]([Li:18])([CH3:19])([CH3:20])[CH3:21].[CH3:15][Li:16].[CH3:41][CH2:42][O:43][CH2:44][CH3:45].[CH3:46][CH2:47][CH2:48][CH2:49][CH3:50].[CH3:51][OH:52].[Cl:22][CH:23]1[CH2:24][c:25]2[c:26]([cH:27][cH:28][cH:29][cH:30]2)[C:31]1=[O:32].[ClH:35].[K+:34].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1.[OH-:33]>>[cH:2]1[c:3]([NH:4][C:5]([C:6]([F:7])([F:8])[F:9])=[O:10])[cH:11][cH:12][cH:13][cH:14]1

Participants

12

Reactant 11

HCID 313Hydrochloric AcidHCID 813Potassium CationHCID 887MethanolHCID 961HydroxideHCID 3283Diethyl EtherHCID 8003PentaneHCID 8028TetrahydrofuranHCID 526932-Chloro-2,3-dihydro-1H-inden-1-oneHCID 4263215N-(2-Bromophenyl)-2,2,2-trifluoroacetamideHCID 178418306HCID 178418306, compoundHCID 178418348HCID 178418348, compound

Product 1

HCID 678812,2,2-Trifluoro-N-phenylacetamide

Sources & evidence

ORD record
ord-aa7a6c93b4614b53b72c0036f8914f47
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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