Water → Ethyl 3-(6-chloropyridin-3-yl)-3-oxopropanoate

HRID 2154806Notes

Reaction equation

HRID 2154806 reaction equation
[C:11]([n:12]1[cH:13][cH:14][n:15][cH:16]1)([n:17]1[cH:18][cH:19][n:20][cH:21]1)=[O:22].[C:24]([CH2:25][C:26]([O-:27])=[O:28])(=[O:29])[O:30][CH2:31][CH3:32].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[O:9])[OH:10])[cH:6][n:7]1.[Mg+:23].[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1.[OH2:33]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[O:10])[CH2:25][C:24](=[O:29])[O:30][CH2:31][CH3:32])[cH:6][n:7]1

Participants

7

Reactant 6

HCID 962WaterHCID 8028TetrahydrofuranHCID 682631,1'-CarbonyldiimidazoleHCID 792226-Chloronicotinic acidHCID 3595298Propanedioic acid, monoethyl esterHCID 178506988HCID 178506988, compound

Product 1

HCID 10421283Ethyl 3-(6-chloropyridin-3-yl)-3-oxopropanoate

Sources & evidence

ORD record
ord-bb62918f59a142768a9eba18b0501b16
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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