Bicarbonate Ion → tert-Butyl 3-(hydroxymethyl)benzylcarbamate

HRID 2156589Notes

Reaction equation

HRID 2156589 reaction equation
[BH4-:32].[C:40](=[O:41])([O-:42])[OH:43].[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12](=[O:13])[NH:14][CH2:15][c:16]1[cH:17][c:18]([C:19](=[O:20])[OH:21])[cH:22][cH:23][cH:24]1.[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[Cl:1][C:2]([O:3][CH2:4][CH3:5])=[O:6].[Li+:33].[Na+:39].[Na+:44].[O:45]1[CH2:46][CH2:47][CH2:48][CH2:49]1.[OH2:50].[S:34]([O-:35])([OH:36])(=[O:37])=[O:38]>>[C:7]([CH3:8])([CH3:9])([CH3:10])[O:11][C:12](=[O:13])[NH:14][CH2:15][c:16]1[cH:17][c:18]([CH2:19][OH:20])[cH:22][cH:23][cH:24]1

Participants

11

Reactant 10

HCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 962WaterHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 10928Ethyl chloroformateHCID 28123BorohydrideHCID 28486Lithium ionHCID 61778Sulfate, hydrogenHCID 27559293-(((tert-Butoxycarbonyl)amino)methyl)benzoic acid

Product 1

HCID 2794814tert-Butyl 3-(hydroxymethyl)benzylcarbamate

Sources & evidence

ORD record
ord-304624d8fb0340b4a1cf85f1f29aab7a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…