Acetic Acid → 6-Bromopyridine-2-carbonitrile
Reaction equation
[Br:12][c:13]1[n:14][c:15]([Br:19])[cH:16][cH:17][cH:18]1.[CH2:2]([Mg+:3])[CH2:4][CH2:5][CH3:6].[CH2:7]([Li:8])[CH2:9][CH2:10][CH3:11].[CH3:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42].[CH3:43][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1.[CH3:50][C:51](=[O:52])[OH:53].[Cl-:1].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1.[c:20]1([CH3:21])[cH:22][cH:23][c:24]([S:25](=[O:26])(=[O:27])[C:29]#[N:30])[cH:28][cH:31]1>>[c:13]1([C:29]#[N:30])[n:14][c:15]([Br:19])[cH:16][cH:17][cH:18]1Participants
10
Sources & evidence
- ORD record
- ord-e26a0ebe2a8343bf8c54ee87c2d360b3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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