Hydrochloric Acid → (SR)-1,4-dibenzyl-3-oxo-piperidine-4-carboxylic acid ethyl ester
Reaction equation
[CH2:23]([c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1)[Br:30].[CH2:4]([c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1)[N:11]1[CH2:12][C:13](=[O:22])[CH:14]([C:17](=[O:18])[O:19][CH2:20][CH3:21])[CH2:15][CH2:16]1.[ClH:3].[H-:2].[Na+:1].[Na+:35].[O-:31][C:32]([OH:33])=[O:34].[O:36]=[CH:37][N:38]([CH3:39])[CH3:40].[OH2:41]>>[CH2:4]([c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1)[N:11]1[CH2:12][C:13](=[O:22])[C:14]([C:17](=[O:18])[O:19][CH2:20][CH3:21])([CH2:23][c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[CH2:15][CH2:16]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-f507359d19644223804359e96685cb83
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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