Hydrochloric Acid → 4-(Benzyloxy)pyridin-2-amine

HRID 2158547Notes

Reaction equation

HRID 2158547 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([Cl:15])[n:12][cH:13][cH:14]1.[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:17][Si:18]([N-:21][Si:19]([CH3:20])([CH3:22])[CH3:23])([CH3:24])[CH3:25].[ClH:31].[Li+:16].[O:34]=[C:35]([CH:36]=[CH:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1)[CH:44]=[CH:45][c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1.[O:52]=[C:53]([CH:54]=[CH:55][c:56]1[cH:57][cH:58][cH:59][cH:60][cH:61]1)[CH:62]=[CH:63][c:64]1[cH:65][cH:66][cH:67][cH:68][cH:69]1.[O:70]=[C:71]([CH:72]=[CH:73][c:74]1[cH:75][cH:76][cH:77][cH:78][cH:79]1)[CH:80]=[CH:81][c:82]1[cH:83][cH:84][cH:85][cH:86][cH:87]1.[Pd:32].[Pd:33]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([NH2:21])[n:12][cH:13][cH:14]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 23938Palladium2×HCID 28486Lithium ionHCID 95417Dibenzylidene acetone3×HCID 3280088Npc316347HCID 534041974-(Benzyloxy)-2-chloropyridine

Product 1

HCID 5200844-(Benzyloxy)pyridin-2-amine

Sources & evidence

ORD record
ord-e8c63c54be43459a975b3477a1f10cae
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…