Acetate → Perampanel

HRID 2159203Notes

Reaction equation

HRID 2159203 reaction equation
[C:1](#[N:2])[c:3]1[c:4](-[c:9]2[c:10](=[O:21])[nH:11][cH:12][c:13](-[c:15]3[n:16][cH:17][cH:18][cH:19][cH:20]3)[cH:14]2)[cH:5][cH:6][cH:7][cH:8]1.[C:42]([O-:43])(=[O:44])[CH3:45].[C:47]([O-:48])(=[O:49])[CH3:50].[CH2:39]([Cl:40])[Cl:41].[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[CH3:51][CH2:52][O:53][C:54](=[O:55])[CH3:56].[Cu+2:46].[NH3:38].[OH2:57].[c:22]1([B:28]([OH:29])[OH:30])[cH:23][cH:24][cH:25][cH:26][cH:27]1>>[C:1](#[N:2])[c:3]1[c:4](-[c:9]2[c:10](=[O:21])[n:11](-[c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[cH:12][c:13](-[c:15]3[n:16][cH:17][cH:18][cH:19][cH:20]3)[cH:14]2)[cH:5][cH:6][cH:7][cH:8]1

Participants

10

Reactant 9

HCID 175Acetate2×HCID 222AmmoniaHCID 962WaterHCID 6344DichloromethaneHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 27099Cupric cationHCID 66827Phenylboronic AcidHCID 223189453-(2-Cyanophenyl)-5-(2-pyridyl)-2(1H)-pyridone

Product 1

HCID 9924495Perampanel

Sources & evidence

ORD record
ord-9c63dc5fa78a4042a713e06c17485f64
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…