Chloride → 4'-(4-Chloro-5-(trifluoromethyl)pyrimidin-2-ylamino)-5'-methoxy-N,2'-dimethylbiphenyl-4-carboxamide
Reaction equation
[C:40]([OH:41])([CH3:42])([CH3:43])[CH3:44].[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[Cl-:45].[Cl-:47].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:9]([F:10])([F:11])[F:12])[c:6]([Cl:8])[n:7]1.[NH2:13][c:14]1[cH:15][c:16]([CH3:32])[c:17](-[c:22]2[cH:23][cH:24][c:25]([C:28](=[O:29])[NH:30][CH3:31])[cH:26][cH:27]2)[cH:18][c:19]1[O:20][CH3:21].[Zn+2:46]>>[c:2]1([NH:13][c:14]2[cH:15][c:16]([CH3:32])[c:17](-[c:22]3[cH:23][cH:24][c:25]([C:28](=[O:29])[NH:30][CH3:31])[cH:26][cH:27]3)[cH:18][c:19]2[O:20][CH3:21])[n:3][cH:4][c:5]([C:9]([F:10])([F:11])[F:12])[c:6]([Cl:8])[n:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-3b7ff51ff32a435289ebce0db146f025
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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