Dimethylformamide → [2-[5-(4-hydroxy-piperidine-1-carbonyl)-thiophen-2-yl]-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-(1-methyl-cyclohexyl)-methanone
Reaction equation
[CH3:1][C:2]1([C:8](=[O:9])[c:10]2[cH:11][n:12]([CH2:27][O:28][CH2:29][CH2:30][Si:31]([CH3:32])([CH3:33])[CH3:34])[c:13]3[n:14][cH:15][c:16](-[c:19]4[cH:20][cH:21][c:22]([C:24](=[O:25])[OH:26])[s:23]4)[n:17][c:18]23)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1.[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[CH3:47][CH2:48][O:49][C:50](=[O:51])[CH3:52].[OH:35][CH:36]1[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]1>>[CH3:1][C:2]1([C:8](=[O:9])[c:10]2[cH:11][n:12]([CH2:27][O:28][CH2:29][CH2:30][Si:31]([CH3:32])([CH3:33])[CH3:34])[c:13]3[n:14][cH:15][c:16](-[c:19]4[cH:20][cH:21][c:22]([C:24](=[O:25])[N:39]5[CH2:38][CH2:37][CH:36]([OH:35])[CH2:41][CH2:40]5)[s:23]4)[n:17][c:18]23)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-89395a1cd72e4fb4a2723d1f24cf1fc9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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