Potassium Cation → 5,5-Dimethyl-1-(2-((4-(3-(trifluoromethyl)-2-thienyl)-2-pyrimidinyl)amino)ethyl)-2,4-imidazolidinedione

HRID 2162398Notes

Reaction equation

HRID 2162398 reaction equation
[CH2:27]([Si:28]([CH2:29][CH3:34])([C:30]([F:31])([F:32])[F:33])[CH2:35][CH3:36])[CH3:37].[CH3:48][N:49]1[CH2:50][CH2:51][CH2:52][C:53]1=[O:54].[Cl:43][CH2:44][Cl:45].[Cu:46][I:47].[F-:25].[I:1][c:2]1[c:3](-[c:7]2[n:8][c:9]([NH:13][CH2:14][CH2:15][N:16]3[C:17](=[O:24])[NH:18][C:19](=[O:23])[C:20]3([CH3:21])[CH3:22])[n:10][cH:11][cH:12]2)[s:4][cH:5][cH:6]1.[K+:26].[O:38]=[CH:39][N:40]([CH3:41])[CH3:42]>>[c:2]1([C:30]([F:31])([F:32])[F:33])[c:3](-[c:7]2[n:8][c:9]([NH:13][CH2:14][CH2:15][N:16]3[C:17](=[O:24])[NH:18][C:19](=[O:23])[C:20]3([CH3:21])[CH3:22])[n:10][cH:11][cH:12]2)[s:4][cH:5][cH:6]1

Participants

9

Reactant 8

HCID 813Potassium CationHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 13387N-methyl-2-pyrrolidoneHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 28179Fluoride IonHCID 4204914Triethyl(trifluoromethyl)silaneHCID 602045261-(2-(4-(3-Iodothiophen-2-yl)pyrimidin-2-ylamino)ethyl)-5,5-dimethylimidazolidine-2,4-dione

Product 1

HCID 602045345,5-Dimethyl-1-(2-((4-(3-(trifluoromethyl)-2-thienyl)-2-pyrimidinyl)amino)ethyl)-2,4-imidazolidinedione

Sources & evidence

ORD record
ord-334cee510afd45dfa5f962dd8547146d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…