Adipoyl chloride → HCID 22754098, compound

HRID 2163151Notes

Reaction equation

HRID 2163151 reaction equation
[NH2:1][C:2]1[C:3]([I:21])=[C:4]([C:13]([NH:15][C:16]([CH3:20])([CH3:19])[CH2:17][OH:18])=[O:14])[C:5]([I:12])=[C:6]([C:10]=1[I:11])[C:7]([OH:9])=[O:8].[C:22](Cl)(=[O:30])[CH2:23][CH2:24][CH2:25][CH2:26][C:27](Cl)=[O:28]>CC(N(C)C)=O>[C:22]([NH:1][C:2]1[C:3]([I:21])=[C:4]([C:13]([NH:15][C:16]([CH3:19])([CH3:20])[CH2:17][OH:18])=[O:14])[C:5]([I:12])=[C:6]([C:10]=1[I:11])[C:7]([OH:9])=[O:8])(=[O:30])[CH2:23][CH2:24][CH2:25][CH2:26][C:27]([NH:1][C:2]1[C:3]([I:21])=[C:4]([C:13]([NH:15][C:16]([CH3:19])([CH3:20])[CH2:17][OH:18])=[O:14])[C:5]([I:12])=[C:6]([C:10]=1[I:11])[C:7]([OH:9])=[O:8])=[O:28]

Participants

4

Reactant 2

HCID 61034Adipoyl chlorideHCID 22754101HCID 22754101, compound

Product 1

HCID 22754098HCID 22754098, compound

Reagents, catalysts & solvents 1

HCID 31374DimethylacetamideSolvent

Procedure

Analogously to Example 10, 5-amino-N-(2-hydroxy-1,1-dimethylethyl)-2,4,6-triiodoisophthalamic acid is reacted with hexanedioic acid dichloride in dimethylacetamide, and the reaction mixture is worked up. The thus-obtained product melts at 280°-281° C., with decomposition.

Sources & evidence

ORD record
ord-67542e65236e4a7dab5358c725ec30a5
Source dataset
uspto-grants-1979_01
Patent number
US04132731

Reaction notes

Loading…