1-Bromo-3-chloropropane → HCID 22752785, compound

HRID 2163525Notes

Reaction equation

HRID 2163525 reaction equation
[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[C:9]([O:12][CH3:13])[CH:10]=2)[C:5](=[O:16])[NH:4][N:3]=1.Br[CH2:18][CH2:19][CH2:20][Cl:21].C(Cl)(Cl)Cl.CO>CN(C)C=O>[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:14][CH3:15])=[C:9]([O:12][CH3:13])[CH:10]=2)[C:5](=[O:16])[N:4]([CH2:18][CH2:19][CH2:20][Cl:21])[N:3]=1

Participants

5

Reactant 3

HCID 80061-Bromo-3-chloropropaneHCID 133270306,7-Dimethoxy-4-methyl-1(2H)-phthalazinoneHCID 21584188Chloroform methanol

Product 1

HCID 22752785HCID 22752785, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

1-[4-Methyl-6,7-dimethoxy-1(2H)-phthalazinone-2-yl]-3-chloropropane was prepared analogous to Example 1 (a) by reaction of 4-methyl-6,7-dimethoxy-1(2H)-phthalazinone with 1-bromo-3-chloro-propane in dimethylformamide. Rf -value (chloroform/methanol = 9/1) : 0.9.

Sources & evidence

ORD record
ord-0b3a432b5db243c08b099a70da56c940
Source dataset
uspto-grants-1979_01
Patent number
US04134980

Reaction notes

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