1-Bromo-3-chloropropane → HCID 22752790, compound

HRID 2163532Notes

Reaction equation

HRID 2163532 reaction equation
[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]3[O:15][CH2:14][CH2:13][O:12][C:9]=3[CH:10]=2)[C:5](=[O:16])[NH:4][N:3]=1.Br[CH2:18][CH2:19][CH2:20][Cl:21].C(Cl)(Cl)Cl.CO>CN(C)C=O>[CH3:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]3[O:15][CH2:14][CH2:13][O:12][C:9]=3[CH:10]=2)[C:5](=[O:16])[N:4]([CH2:18][CH2:19][CH2:20][Cl:21])[N:3]=1

Participants

5

Reactant 3

HCID 80061-Bromo-3-chloropropaneHCID 21584188Chloroform methanolHCID 22752805HCID 22752805, compound

Product 1

HCID 22752790HCID 22752790, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

1-[4-Methyl-6,7-ethylenedioxy-1(2H)-phthalazinone-2-yl]-3-chloro-propane was prepared analogous to Example 1 (a) by reaction of 4-methyl-6,7-ethylenedioxy-1(2H)-phthalazinone with 1-bromo-3-chloro-propane in dimethylformamide. Rf -value (chloroform/methanol = 19/1) : 0.9.

Sources & evidence

ORD record
ord-58d6754e101a4c689b8fa2b5a21ecb90
Source dataset
uspto-grants-1979_01
Patent number
US04134980

Reaction notes

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