Propyl mercaptan → HCID 20301879, compound

HRID 2164041Notes

Reaction equation

HRID 2164041 reaction equation
[Cl:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[C:6](Cl)=[CH:5][C:3]=1[NH2:4].[CH2:13]([SH:16])[CH2:14][CH3:15].[C:17]1([SH:23])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[Cl:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[C:6]([S:16][CH2:13][CH2:14][CH3:15])=[CH:5][C:3]=1[NH2:4].[Cl:1][C:2]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[C:6]([S:23][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:5][C:3]=1[NH2:4]

Participants

7

Reactant 4

HCID 7848Propyl mercaptanHCID 7969ThiophenolHCID 11430Potassium CarbonateHCID 231082,5-Dichloro-4-nitroaniline

Product 2

HCID 20301879HCID 20301879, compoundHCID 20301893HCID 20301893, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Similarly, 2.5-dichloro-4-nitroaniline is allowed to react with n-propyl mercaptan and thiophenol in dimethylformamide at 100° C. in the presence of potassium carbonate to afford 2-chloro-4-nitro-5-n-propylthioaniline, m.p. 125°-127° C., and 2-chloro-4-nitro-5-phenylthioaniline, m.p. 163°-166° C.

Sources & evidence

ORD record
ord-0a013e0dc62443778cee55a2c9273107
Source dataset
uspto-grants-1979_01
Patent number
US04137310

Reaction notes

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