反应详情

温度

55 °C

Al mixture of 27.5 g of selenium dioxide, 160 ml of dioxane and 5.5 ml of water was heated at 55° C. until solution was complete. A 31.54 g portion of 2-acetylthiophene was added and the mixture was refluxed for 4 hours, then cooled, filtered and evaporated under reduced pressure. The residue was distilled giving 24.5 g of 2-thiopheneglyoxylaldehyde.

1. temperaturethe mixture was refluxed for 4 hours
2. temperaturecooled
3. filtrationfiltered
4. customevaporated under reduced pressure
5. distillationThe residue was distilled