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HRID2165650

反应详情

EQUATION

反应方程式

HRID 2165650 的结构方程式

REACTANTS

反应物

3
结构：CCI
HCID6340

Ethane, iodo-

C2H5I

结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：CCOC(=O)c1c[nH]c2c(F)c(F)c(F)cc2c1=O
HCID2733972

3-Quinolinecarboxylic acid, 1,4-dihydro-4-oxo-6,7,8-trifluoro-, ethyl ester

C12H8F3NO3

PRODUCTS

生成物

1
结构：CCOC(=O)c1cn(CC)c2c(F)c(F)c(F)cc2c1=O
HCID5140913

Ethyl 1-ethyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate

C14H12F3NO3

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

A 49.1 g portion of 6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, ethyl ester was reacted with 85 g of potassium carbonate, 266 g of ethyl iodide and 600 ml of dimethylformamide, giving 1-ethyl-1,4-dihydro-6,7,8-trifluoro-4-oxo-3-quinolinecarboxylic acid, ethyl ester.