3-Chloro-2-methyl-1-propene → HCID 23039515, compound

HRID 2166338Notes

Reaction equation

HRID 2166338 reaction equation
[Cl:1][C:2]1[C:3](=[O:9])[NH:4][N:5]=[CH:6][C:7]=1[Cl:8].Cl[CH2:11][C:12]([CH3:14])=[CH2:13].C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[Cl:1][C:2]1[C:3](=[O:9])[N:4]([CH2:13][C:12]([CH3:14])=[CH2:11])[N:5]=[CH:6][C:7]=1[Cl:8]

Participants

5

Reactant 3

HCID 112413-Chloro-2-methyl-1-propeneHCID 11430Potassium CarbonateHCID 732474,5-Dichloro-3-hydroxypyridazine

Product 1

HCID 23039515HCID 23039515, compoundYield 36.9%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
40 °C

Procedure

To 50 ml of N,N-dimethylformamide were suspended 10 g of 4,5-dichloro-3(2H)-pyridazinone, 27 g of 3-chloro-2-methylpropene and 8.4 g of potassium carbonate. The mixtured solution was stirred for 5 hours at 40° C. Then, the procedures in Preparation Example 2 were repeated to give 4.9 g of the intended compound.

Workup

  1. customThen, the procedures in Preparation Example 2

Sources & evidence

ORD record
ord-112dcfeb10c242c68c5acaaeed4a5f8e
Source dataset
uspto-grants-1990_07
Patent number
US04945091

Reaction notes

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