反应详情

The product from Step C, 78 mg, is dissolved in 0.4 ml of anisole and treated at 0° C. for 10 minutes with 2.0 ml of trifluoroacetic acid (TFA). The TFA and anisole are pumped off at 20° C., and water and CH2Cl2 are added to the residue. The water layer is separated and evaporated, affording 66 mg of pure product.

1. customare pumped off at 20° C.
2. customThe water layer is separated
3. customevaporated