反应详情

1-(3,5-Dihydroxyphenyl)ethanone (3 g) and methyl iodide (2.80 g) were dissolved in DMF (40 ml), and sodium hydride (568 mg) was added. After stirring at RT for 2 h, the DMF was drawn off. The residue was taken up in EA and washed with water, dried, filtered and concentrated. The residue was purified using silica gel (89 g cartridge, n-heptane/EA 0-50% within 30 min). 1.12 g of the title compound were obtained.

1. washwashed with water
2. customdried
3. filtrationfiltered
4. concentrationconcentrated
5. customThe residue was purified
6. customsilica gel (89 g cartridge, n-heptane/EA 0-50% within 30 min)