反应详情

To a solution of compound 13 (0.23 g, 1.03 mmol) in 15 ml of HCl solution in 1,4-dioxane was added 4-nitrobenzaldehyde (0.16 g, 1.06 mmol) in one portion. After refluxing for 5 hours, the solvent was removed under reduced pressure. The residue was washed with cold ethanol three times, and dried to give the product 14 (0.21 g, 66%).

1. temperatureAfter refluxing for 5 hours
2. customthe solvent was removed under reduced pressure
3. washThe residue was washed with cold ethanol three times
4. customdried