反应详情

A mixture of 2-bromo-5-nitro-p-xylene (200 g), 2-benzo[b]thiopheneboronic acid (200 g), (Ph3P)4Pd (0.36 g) in toluene (60 ml) and ethanol (22 ml) was heated to reflux overnight. Ethyl acetate and water were added and the organic phase was separated. The organic phase was washed with water, dried (MgSO4) and filtered through a pad of silica to give the title product.

1. temperaturewas heated
2. temperatureto reflux overnight
3. customthe organic phase was separated
4. washThe organic phase was washed with water
5. dry with materialdried (MgSO4)
6. filtrationfiltered through a pad of silica