Hydrochloric Acid → HCID 18475842, compound

HRID 2187882Notes

Reaction equation

HRID 2187882 reaction equation
C(OC([NH:8][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]([O:19][Si:20]([C:33]([CH3:36])([CH3:35])[CH3:34])([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[CH:17]=2)[CH:12]=[CH:11][CH:10]=1)=O)(C)(C)C.CCOCC.[ClH:42]>CCOC(C)=O>[ClH:42].[NH2:8][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]([O:19][Si:20]([C:33]([CH3:36])([CH3:35])[CH3:34])([C:21]3[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=3)[C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[CH:17]=2)[CH:12]=[CH:11][CH:10]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 18475884HCID 18475884, compound

Product 1

HCID 18475842HCID 18475842, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A solution of 1-(tert-butoxycarbonylamino)-7-(tert-butyldiphenylsilyloxy)naphthalene, as described above in Step B, (1.54 g, 3.09 mmol) in EtOAc (80 mL) and Et2O (20 mL) at ambient temperature was saturated with HCl (g). After 1 hr, the mixture was concentrated in vacuo to yield the desired product as a pale solid.

Workup

  1. customat ambient temperature
  2. concentrationthe mixture was concentrated in vacuo

Sources & evidence

ORD record
ord-07d69559853b46c799200cc871c93321
Source dataset
uspto-grants-2002_06
Patent number
US06410534B1

Reaction notes

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