Dimethylformamide → HCID 54219924, compound

HRID 2198570Notes

Reaction equation

HRID 2198570 reaction equation
O([C:8]([C:10]1[CH:19]=[CH:18][C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11]=1[OH:20])=[O:9])C1C=CC=CC=1.[S:21]([OH:31])(=[O:30])([C:23]1[CH:28]=[CH:27][C:26]([NH2:29])=[CH:25][CH:24]=1)=[O:22].C[N:33](C=O)C>C(N(CC)CC)C>[S:21]([C:23]1[CH:24]=[CH:25][C:26]([NH:29][NH:33][C:8]([C:10]2[CH:19]=[CH:18][C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:11]=2[OH:20])=[O:9])=[CH:27][CH:28]=1)([OH:31])(=[O:30])=[O:22]

Participants

5

Reactant 3

HCID 6228DimethylformamideHCID 8479Sulfanilic acidHCID 67236Phenyl 1-hydroxy-2-naphthoate

Product 1

HCID 54219924HCID 54219924, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Conditions

Temperature
170 °C

Procedure

To 13.2 g of 2-phenoxycarbonyl-1-naphthol, 8.6 g of sulfanilic acid, 20 ml of DMF and 14 ml of triethylamine were added. The mixture was stirred at 170° C. for 5 hours. The mixture was concentrated at reduced pressure and methanol was added to the residue. The crystals thus-precipitated were collected by filtration.

Workup

  1. concentrationThe mixture was concentrated at reduced pressure and methanol
  2. additionwas added to the residue
  3. customThe crystals thus-precipitated
  4. filtrationwere collected by filtration

Sources & evidence

ORD record
ord-efbd86e8c1d24a2e93d32639a5a26f3a
Source dataset
uspto-grants-1982_11
Patent number
US04358526

Reaction notes

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