Nitrogen → 2-Propenoic acid, 3-phenyl-

HRID 22096Notes

Reaction equation

HRID 22096 reaction equation
CO[C:3]1[CH:17]=[CH:16][CH:15]=[CH:14][C:4]=1[C:5](OC)=[C:6](OC)[C:7]([OH:9])=[O:8].[OH-].[Na+].N#N>CS(C)=O>[C:7]([OH:9])(=[O:8])[CH:6]=[CH:5][C:4]1[CH:3]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

5

Reactant 3

HCID 947NitrogenHCID 14798Sodium HydroxideHCID 54572276Trimethoxy cinnamic acid

Product 1

HCID 87842-Propenoic acid, 3-phenyl-

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

4.35 g of trimethoxy cinnamic acid and 100 mg of sodium hydroxide were dissolved in 5 ml of DMSO, and the mixture was stirred and heated to 90° C. under a flow of N2 gas. Water in the system was removed under low pressure condition. 10 g of glycidol was added, heating and agitation was carried out for 3 hours, and then the adduct of cinnamic acid and glycerin was obtained.

Workup

  1. customWater in the system was removed under low pressure condition
  2. addition10 g of glycidol was added
  3. temperatureheating

Sources & evidence

ORD record
ord-6d8fcbd9ccb7401eb76af8001a00d099
Source dataset
uspto-grants-1995_06
Patent number
US05426210

Reaction notes

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