4-Chloro-3-pyridinesulphonamide → HCID 10727418, compound

HRID 2210427Notes

Reaction equation

HRID 2210427 reaction equation
Cl[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[S:8]([NH2:11])(=[O:10])=[O:9]>C(N)CC.C(O)(C)C.O>[CH2:4]([NH:5][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[S:8]([NH2:11])(=[O:10])=[O:9])[CH2:3][CH3:2]

Participants

5

Reactant 1

HCID 1184264-Chloro-3-pyridinesulphonamide

Product 1

HCID 10727418HCID 10727418, compound

Reagents, catalysts & solvents 3

HCID 962WaterSolventHCID 3776IsopropanolSolventHCID 7852PropylamineSolvent

Procedure

2 g of 4-chloropyridine-3-sulfonamide are dissolved in 10 cm3 of n-propylamine and 10 cm3 of isopropanol. The mixture is brought to reflux for 2 hours, the solution is then cooled and the solvent is evaporated. The solid obtained is redispersed in water (20 cm3). The insoluble material is collected on the filter, washed with water and dried.

Workup

  1. temperatureto reflux for 2 hours
  2. temperaturethe solution is then cooled
  3. customthe solvent is evaporated
  4. customThe solid obtained
  5. customThe insoluble material is collected on the filter
  6. washwashed with water
  7. customdried

Sources & evidence

ORD record
ord-d43689a321844f498db0a0431ccd5cff
Source dataset
uspto-grants-1995_10
Patent number
US05459138

Reaction notes

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