Potassium Carbonate → HCID 15278662, compound

HRID 2210677Notes

Reaction equation

HRID 2210677 reaction equation
C(=O)([O-])[O-].[K+].[K+].Cl.[F:8][C:9]([F:25])([F:24])[C:10]1[CH:11]=[C:12]([N:17]2[CH:21]=[C:20]([CH3:22])[S:19][C:18]2=[NH:23])[CH:13]=[CH:14][C:15]=1[F:16]>C(OCC)(=O)C>[F:24][C:9]([F:8])([F:25])[C:10]1[CH:11]=[C:12]([N:17]2[CH:21]=[C:20]([CH3:22])[S:19][C:18]2=[NH:23])[CH:13]=[CH:14][C:15]=1[F:16]

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 67805665HCID 67805665, compound

Product 1

HCID 15278662HCID 15278662, compoundYield 79.2%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

To a mixture of ethyl acetate (50 ml) and aqueous potassium carbonate (20 ml), 3-(3-trifluoromethyl-4-fluorophenyl)-5-methyl-2-iminothiazoline hydrochloride (1 g) was added; and the mixture was stirred. The organic layer was isolated and dried over anhydrous magnesium sulfate. The solvent was removed under reduced pressure to give 0.7 g of 3-(3-trifluoromethyl-4-fluorophenyl)-5-methyl-2-iminothiazoline as an oil.

Workup

  1. additionwas added
  2. customThe organic layer was isolated
  3. dry with materialdried over anhydrous magnesium sulfate
  4. customThe solvent was removed under reduced pressure

Sources & evidence

ORD record
ord-58c49572741c4ae284c3cc69f2a1e5df
Source dataset
uspto-grants-1995_10
Patent number
US05459277

Reaction notes

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