Pyridine-2-carbonitrile → Picolinimidohydrazide

HRID 2213322Notes

Reaction equation

HRID 2213322 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1)#[N:2].O.[NH2:10][NH2:11]>C(O)C>[N:4]1[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=1[C:1](=[N:10][NH2:11])[NH2:2]

Participants

4

Reactant 2

HCID 7522Pyridine-2-carbonitrileHCID 24654Hydrazine hydrate (1:1)

Product 1

HCID 70493Picolinimidohydrazide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-Cyanopyridine (5.2 g, 50 mmol) and hydrazine hydrate (2.95 g, 50 mmol) were mixed and a small amount of ethanol was added to obtain a clear solution. After standing overnight at ambient temperature, the resulting white crystals were collected by filtration. The resulting product was washed with diethyl ether and dried in the air to afford pyridine-2-carbohydrazonamide.

Workup

  1. customto obtain a clear solution
  2. filtrationthe resulting white crystals were collected by filtration
  3. washThe resulting product was washed with diethyl ether
  4. customdried in the air

Sources & evidence

ORD record
ord-c839c168255a492e873e23d1f0d201dc
Source dataset
uspto-grants-2006_09
Patent number
US07105548B2

Reaction notes

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