Hydrogen Peroxide → 2-Octanone

Temperature

90 °C

Platinum black (1.50 g, 7.7 mmol) and 2-octanol (100 g, 768 mmol) were mixed and stirred at 90° C. for 10 minutes. A 30% aqueous hydrogen peroxide solution (104 g, 918 mmol) was gradually added dropwise to the mixed solution, followed by stirring at 90° C. for 20 hours, and then the reaction solution was cooled to room temperature. The organic phase was separated and washed with 100 ml of a saturated aqueous sodium thiosulfate solution, followed by distillation, and 2-octanone was obtained in yield of 95% (93.9 g, 730 mmol).

1. stirringby stirring at 90° C. for 20 hours
2. temperaturethe reaction solution was cooled to room temperature
3. customThe organic phase was separated
4. washwashed with 100 ml of a saturated aqueous sodium thiosulfate solution
5. distillationfollowed by distillation

ORD record

ord-1df57ad5ccd142a5986bea7cc5654f50

Source dataset

uspto-grants-2006_09

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US07109379B2