反应详情

温度

100 °C

To a solution of 1-(4′-(2-tetrahydropyranyloxy)phenyl)-3-bromopropane 3C (4.2 g) in anhydrous dimethylformamide (11.3 mL) is added triphenylphosphine (6.12 g). The reaction mixture is stirred under nitrogen at 100° C. overnight. The reaction mixture is then cooled to room temperature. The white precipitate is filtered and washed with ethyl acetate, then dried under vacuum.

1. temperatureThe reaction mixture is then cooled to room temperature
2. filtrationThe white precipitate is filtered
3. washwashed with ethyl acetate
4. customdried under vacuum