Hydrochloric Acid → HCID 13060370, compound

HRID 2231792Notes

Reaction equation

HRID 2231792 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([SH:8])=[CH:4][CH:3]=1.[CH3:9][O:10][C:11]1[CH:18]=[CH:17][C:14]([CH:15]=O)=[CH:13][CH:12]=1.[Cl-:19].[Ca+2].[Cl-].Cl>C(Cl)Cl>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH:15]([Cl:19])[C:14]2[CH:17]=[CH:18][C:11]([O:10][CH3:9])=[CH:12][CH:13]=2)=[CH:4][CH:3]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 7815p-ChlorothiophenolHCID 312444-MethoxybenzaldehydeHCID 5284359Calcium Chloride

Product 1

HCID 13060370HCID 13060370, compoundYield 97.4%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

144 g of 4-chlorothiophenol in 300 ml of methylene chloride are initially introduced, and 136 g of 4-methoxybenzaldehyde in 300 ml of methylene chloride are added. After the addition of 80 g of calcium chloride, dry hydrogen chloride is introduced into the mixture for 6 hours. After the mixture has stood overnight, it is filtered and the methylene chloride solution is concentrated. The solid product is recrystallised from petroleum ether. 210 g of crystals of melting point 76° to 77° C. are obtained.

Workup

  1. additionis introduced into the mixture for 6 hours
  2. filtrationit is filtered
  3. concentrationthe methylene chloride solution is concentrated
  4. customThe solid product is recrystallised from petroleum ether

Sources & evidence

ORD record
ord-d170afc528f84e0986f9e6b161169684
Source dataset
uspto-grants-1988_11
Patent number
US04783562

Reaction notes

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