反应详情

Method B (24 h at 60° C.); starting materials: 7,8,9,10-tetrahydro-2-[3-(methanesulfonyloxy)propoxy]-3-methoxy-6H-dibenzo[b,d]pyran-6-one (example 80) and 1-phenylpiperazine; yield 94%; fusion point 104°-106° C. (from TBME and isopropanol). Fumarate: method E; yield 92%; fusion point 160°-161° C. (from ethanol and acetone).

1. customMethod B (24 h at 60° C.)